MyBioSource.com's CYP2B6 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot. The CYP2B6 Antibody (Center) was generated using CPB6, and CYP2B6 as the antigen and it reacts with Human.
Description
This gene, CYP2B6, encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
This protein localizes to the endoplasmic reticulum and its
expression is induced by phenobarbital. The enzyme is known to
metabolize some xenobiotics, such as the anti-cancer drugs
cyclophosphamide and ifosphamide. Transcript variants for this gene
have been described; however, it has not been resolved whether
these transcripts are in fact produced by this gene or by a closely
related pseudogene, CYP2B7. Both the gene and the pseudogene are
located in the middle of a CYP2A pseudogene found in a large
cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F
subfamilies on chromosome 19q